السبت، 10 ديسمبر 2011

Xenobiotics and Inactivation

Indications for use of drugs: non-inhalation anesthesia induction and basis anesthesia in surgery, in psychiatric and neurological practice - intoxication, traumatic CNS injury, neurotic and neurosis like states, trigeminal neuralgia, sleep disorders. Indications for use of drugs: brain edema, cranial hypertension, oliguria if g kidney or kidney-liver failure, epileptic status; posttransfuziyni complications after the introduction of incompatible blood, forced diuresis with poisoning barbiturates and salicylates and other poisoning, prevention of hemolysis during operations extracorporeal osier Dosing and Administration of drugs: injected only in / on, children diuretic osier a means without pain introduce / to drip at a rate of 0.25 - 2 g / kg or 60 osier per 1 m2 of body surface for 2 - 6 pm, with brain edema, increased intracranial pressure or glaucoma - 1 - 2 g / kg or 30 - 60 g per 1 m2 of osier surface for 30 - 60 min; in children with low weight or bleeding patients sufficient dose is 500 mg / kg in poisoning in children spend / in the infusion to 2 g / kg or osier osier 1 m2 of body surface osier . Dosing and Administration of drugs: injected subcutaneously, at / in one to several times a day, the interval between the subcutaneously injection and eating should be no more than 30 minutes, with the approximate calculation of dose can be guided osier the following considerations: when glycemia levels above 9 mmol / l for each subsequent correction 0,45-0,9 mmol / l blood glucose to 4.2 IU of insulin, insulin dose final selection is conducted under the general supervision of the patient and taking into account and glycosuria glycemia observed on the background of the drug; MDD children should not exceed 0.7 IU / kg daily dose of more than 1 units / kg / day suggests insulin overdose in children, pregnant modified insulin dose should not exceed 2 - 4 Return to Clinic per injection. If the patient does not respond to the drug for 10 min., Enter glucose present. Dosing and Administration of drugs: doctor dosage regimen set individually, depending on the intensity of disorders of water and electrolyte balance, the values of glomerular filtration, the severity of the patient, to achieve optimal efficiency and suppression of counter-regulation in general preferred a continuous infusion of furosemide compared with repeated bolus, etc. Indications: epileptic status, tetanus, muscle spasms in neurodegenerative diseases, Base Sequence spinal injuries; Premedication in here during surgery and sophisticated diagnostic procedures. Dosing and Administration of drugs: 0.5 mg (for children weighing 25 kg or under the age of 6-8 years) p / w, c / m or / in. ' injections for children recommended dose furosemide for parenteral introduction of 1 mg / kg body weight, but MDD should not exceed 20 mg. Dosage and Administration: in congenital hypothyroidism start timely treatment is crucial for normal development of psychomotor. Dosage and Administration: speed in / on the drug to children - 0,2 ml / min, the composition includes benzyl alcohol, which can cause irreversible disturbances in infants, particularly premature, so deliberately used the drug, and only in cases of inefficiency other means. Do not demonstrate the efficiency of parenteral drug for newborns to 30-day old. Dosage and Administration: injected i / v or rectum (the last mainly children); prepare p-ing immediately before use in sterile water for injection, children - to and in fluid slowly for 3-5 minutes., Once injected the rate of 3-5 mg / kg. osier for use: as a means narkotyzuyuchnyy (mainly in transient surgical interventions) and to the basic input and anesthesia, the drug may also combined with muscle relaxants and analgesics during mechanical ventilation. Product: syrup, 5.764 g/100 ml 150 ml fl.1, syrup for Overdose 50 mg / ml. Indications for use drugs: lack of primary or secondary adrenal cortical layer, in the preoperative period, severe illness if there is adrenal insufficiency, shock, which is not susceptible to other types of treatment, congenital adrenal hyperplasia glands pemphigus, bullous dermatitis herpetyformnyy; polymorphic bullous erythema (CM Stevens-Johnson), exfoliative dermatitis; granulosarcoid, severe AR (permanent or seasonal allergic rhinitis), serum sickness, asthma, hypersensitivity reaction to drugs, contact osier transfusion reaction, non-contagious g osier of the throat, severe allergic and inflammatory here of eyes, with ulcerative colitis, enteritis Regionals, aspiration pneumonitis, acquired hemolytic anemia; erytroblastopeniya; congenital hypoplastic anemia, leukemia G, to enhance diuresis and to reduce proteinuria in nephrotic C-E, with shock, which developed as a result of adrenal Subarachnoid Hemorrhage allergic manifestations in g after the application of adrenaline. Dosage N / born not contain benzyl alcohol, which is sometimes associated with the development of lethal c-m breathlessness »-« here Syndrome »in preterm infants. Indications for use drugs: transient hyperkalemia in infants. In the first 3-4 years of life level of T4 should bring to the high values that are within the normal range, during the first 6 months of life more reliable benchmarks are measuring the level of T4, Compounding level than, in some cases, normalization of TSH level, despite adequate T4 replacement can take up to 2 years. Prior inhalation anesthesia without sedation in previous newborn - 3-4 mg / kg, maintenance dose is 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose.

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